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Melanocortin

MT-2

Synthetic cyclic α-MSH analog studied across melanocortin receptor research models.

Educational / research context only. Research use only — not for human consumption.

Mechanism

MT-2 is a non-selective agonist at melanocortin receptors (MC1R–MC5R) with high affinity for MC1R and MC4R. In research models it is studied for effects on melanogenesis, appetite signaling, and central melanocortin pathways.

Discovery

Developed at the University of Arizona in the 1980s as part of a program on stabilized α-melanocyte-stimulating hormone analogs.

Research Status

Widely used research probe for melanocortin signaling. Broad-receptor profile makes it a common reference tool relative to selective MC-subtype agonists.

Quality Notes

Correct cyclic disulfide structure is essential; open-ring impurities alter receptor activity. Ares MT-2 is third-party tested with COA.

Related research

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