MT-2
Synthetic cyclic α-MSH analog studied across melanocortin receptor research models.
Mechanism
MT-2 is a non-selective agonist at melanocortin receptors (MC1R–MC5R) with high affinity for MC1R and MC4R. In research models it is studied for effects on melanogenesis, appetite signaling, and central melanocortin pathways.
Discovery
Developed at the University of Arizona in the 1980s as part of a program on stabilized α-melanocyte-stimulating hormone analogs.
Research Status
Widely used research probe for melanocortin signaling. Broad-receptor profile makes it a common reference tool relative to selective MC-subtype agonists.
Quality Notes
Correct cyclic disulfide structure is essential; open-ring impurities alter receptor activity. Ares MT-2 is third-party tested with COA.
Related research
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