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Growth Hormone

Ipamorelin

Selective pentapeptide GH secretagogue studied for ghrelin-receptor-driven GH release.

Educational / research context only. Research use only — not for human consumption.

Mechanism

Ipamorelin is a selective agonist at the growth hormone secretagogue receptor (GHSR-1a, the ghrelin receptor). Research models show GH release without significant cross-activation of ACTH, cortisol, or prolactin pathways at study concentrations.

Discovery

Identified at Novo Nordisk in the late 1990s during screening for selective ghrelin-receptor agonists with minimal off-target endocrine activity.

Research Status

Common reference compound for the ghrelin-receptor arm of GH research. Frequently paired with GHRH analogs in comparative pulse studies.

Quality Notes

Correct pentapeptide sequence and Aib-residue integrity are essential. Ares ipamorelin ships with third-party COA.

Related research

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