Epithalon Research Hub — Telomerase & Pineal Research Studies
Epithalon (also Epitalon or Epithalone) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from research on the pineal peptide Epithalamin. It is widely cited in telomerase-activity and longevity research.
What this hub covers
- Tetrapeptide Ala-Glu-Asp-Gly structure
- Telomerase activity and chromosomal stability literature
- Pineal gland / melatonin axis research models
- Comparisons to Pinealon and the broader peptide-bioregulator literature
- Reconstitution and storage
Epithalon research articles
All research →Epitalon vs SS-31 — Research Comparison (2026)
Epitalon vs SS-31 (elamipretide): pineal/telomerase research peptide vs mitochondria-targeted cardiolipin peptide.
Read article →Epitalon Reconstitution & Storage — Research Guide (2026)
Epitalon reconstitution and storage guide: vial sizes, diluent volumes, U-100 syringe math, and stability windows for laboratory research.
Read article →Epitalon Safety Profile — Research Reference Guide (2026)
Epitalon (epithalon) safety profile: tolerability, telomerase considerations, contraindications, and monitoring.
Read article →Epithalon Benefits and Side Effects: A Research Guide
Published research on Epithalon (Epitalon) — the synthetic pineal tetrapeptide studied for telomerase activation, melatonin-axis restoration, and geroprotective outcomes in the Khavinson literature.
Read article →Epithalon Research Overview
Epithalon (Epitalon): telomerase activation, telomere biology, pineal regulation, and the anti-aging evidence base from cellular and animal research models.
Read article →Pinealon Research Overview
Pinealon (Ala-Glu-Asp; AED) is the smallest member of the Khavinson bioregulatory tripeptide family, derived from pineal gland tissue and studied for CNS neuroprotection, retinal cell protection, circadian rhythm support, and — due to its minimal size — viable intranasal delivery for direct central nervous system targeting.
Read article →Epitalon vs NAD+: Longevity Research Comparison
Compare Epitalon tetrapeptide and NAD+ coenzyme research in cellular aging and longevity models.
Read article →Epitalon Mechanism of Action — Telomerase Activation &
Proposed mechanisms of the synthetic pineal-tetrapeptide epitalon: telomerase reactivation, telomere length effects, pineal melatonin support and longevity-model data.
Read article →Epithalon Dosing & Protocols — Research Reference
Reference dose ranges, reconstitution math, and cycle-based scheduling drawn from the published Epithalon telomerase and pineal-research record.
Read article →Epithalon research FAQ
- What is Epithalon?
- Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from research on the natural pineal peptide preparation Epithalamin. It is widely studied in telomerase-activity and ageing-research models.
- What does the published research focus on?
- Telomerase activation in somatic cells, normalisation of melatonin rhythms in rodent models, and longevity endpoints in long-running animal studies are the most-cited areas — see the Epithalon research overview for representative citations.
- How does Epithalon compare to Pinealon?
- Both are short peptide bioregulators with pineal-related research origins. Pinealon (Glu-Asp-Arg) is studied more in neuroprotection contexts; Epithalon's research footprint is dominated by telomerase and longevity models.
- How is Epithalon stored?
- Lyophilized Epithalon is stable at 2–8 °C protected from light. After reconstitution, refrigerate and use within the COA's documented window.
All content on this hub is provided strictly for laboratory research purposes. Compounds listed are not for human or veterinary consumption. See our research-use disclosure for full terms.