DSIP
Documentation & standards
- How to Read a Peptide Certificate of Analysis (COA)
- Peptide Storage and Handling: Temperature, Light and Stability
- Research-Use-Only Compliance: What the Label Obligates
Naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) examined in sleep-architecture, neuroendocrine, and HPA-axis stress-signalling research endpoints.
Mix and match any items — discount applies automatically at checkout.
Reminder email when it's time to reorder. No card on file. Cancel anytime from your account — or email support@aresresearchlab.com.
Earn 24 loyalty points on this purchase · 100 pts = $5 off
Create a Research Account to unlock full batch data, COAs, and priority releases.
Intended strictly for controlled laboratory receptor and pathway research.
What is DSIP (Delta Sleep-Inducing Peptide)?
DSIP is a naturally occurring nonapeptide — Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, approximately 849.9 Da — first isolated from rabbit cerebral venous blood in the 1970s and detected in hypothalamic, limbic, pituitary, and peripheral tissue.
Published research with DSIP examines sleep-architecture EEG measurements in animal models, hypothalamic-pituitary-adrenal axis readouts such as ACTH and corticosterone under experimental stress, circadian and thermoregulatory parameters, and oxidative-stress markers in tissue models. No dedicated high-affinity DSIP receptor has been characterised, so mechanistic accounts in the literature — GABAergic modulation, opioid-system interaction, hypothalamic CRH signalling — remain provisional. The record is also uneven: effects reported in animal models have not consistently reproduced across laboratories. This page describes the compound and those studied endpoints only.
DSIP COA and batch verification
A Janoshik Analytical report dated June 2026 for DSIP 15 mg is on file and displayed with this listing. Verification for research material supplied under this catalog follows the documented process: match the identifier on the received unit through the public batch lookup, and review the published verification standards before use.
DSIP research material specifications
| Compound | DSIP (Delta Sleep-Inducing Peptide) |
|---|---|
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| Class | Naturally occurring nonapeptide |
| Molecular weight | ≈849.9 Da (9 residues) |
| Endpoints studied | Sleep-architecture EEG measures, neuroendocrine readouts, HPA-axis and stress signalling |
| Receptor status | No dedicated high-affinity receptor characterised in published literature |
| Purity specification | ≥99% |
| Physical form | Lyophilized powder in a sealed glass vial |
| Available vial sizes | 2 mg, 5 mg, 10 mg, 12 mg |
| Attached report | DSIP 15 mg — Janoshik Analytical (June 2026) |
| Storage | Refrigerated, dry, and protected from light; follow batch documentation |
Nonapeptide research context
Kovalzon VM, Strekalova TV, “Delta sleep-inducing peptide (DSIP): a still unresolved riddle” (2006), PMID 16539679. Listed for characterisation context only.
DSIP research questions
+What is DSIP?
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, first isolated from rabbit cerebral venous blood in the 1970s. It is supplied here as laboratory research material.
+Why is DSIP called a delta sleep-inducing peptide?
The name reflects the experimental context in which the peptide was first isolated — cerebral venous blood collected during delta-wave EEG activity — rather than a settled account of its function. Later literature describes a broader neuroendocrine and stress-signalling profile, and the sleep-architecture record itself is mixed across species and laboratories.
+Which endpoints does published DSIP research examine?
Reported endpoints include EEG sleep-architecture measurements in animal models, hypothalamic-pituitary-adrenal axis readouts such as ACTH and corticosterone under experimental stress, circadian and thermoregulatory measurements, and oxidative-stress markers in tissue models.
+Is a specific DSIP receptor characterised?
No. Despite decades of published work, no dedicated high-affinity DSIP receptor has been definitively identified. Proposed mechanisms in the literature involve GABAergic and opioid-system modulation and effects on hypothalamic corticotropin-releasing hormone signalling, and are described as provisional.
+Is a DSIP analytical report available?
Yes. A Janoshik Analytical report (June 2026) for DSIP 15 mg is on file and displayed with this listing. Researchers should still match the identifier on the received unit through the public batch lookup and review the verification standards page.
+Which DSIP formats are offered?
DSIP is supplied as sealed lyophilized research material in 2 mg, 5 mg, 10 mg, and 12 mg vials. Current offers appear on this page.
+What is the listed purity specification?
The catalog specification is ≥99%. A specification is not the same as a batch result, so documentation associated with the received unit should be reviewed separately.
Read the DSIP research
Research reference for DSIP (Delta Sleep-Inducing Peptide): nonapeptide sequence, distribution, and the sleep-architecture, neuroendocrine and HPA-axis endpoints examined in published literature.
Read article →The DSIP molecule itself: the Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu nonapeptide sequence, analytical identity, endogenous distribution, and the neuroendocrine and stress-signalling pathways published research has examined.
Read article →Researcher Reviews
Sign in with the account that placed your order to leave a verified review.
Ask the Lab
No public questions yet — be the first to ask.
Independent Certificate of Analysis
Independently tested by Janoshik Analytical. Verified and batch-tracked by Ares Research. Additional reports available upon request.
No fillers. No shortcuts. Only verified compounds.