KPV
Documentation & standards
- How to Read a Peptide Certificate of Analysis (COA)
- Peptide Storage and Handling: Temperature, Light and Stability
- Research-Use-Only Compliance: What the Label Obligates
KPV is the Lys-Pro-Val C-terminal tripeptide fragment of α-MSH, supplied for cellular anti-inflammatory-signaling and immune-modulation research endpoints.
Mix and match any items — discount applies automatically at checkout.
Reminder email when it's time to reorder. No card on file. Cancel anytime from your account — or email support@aresresearchlab.com.
Earn 39 loyalty points on this purchase · 100 pts = $5 off
Create a Research Account to unlock full batch data, COAs, and priority releases.
Intended strictly for controlled laboratory receptor and pathway research.
What is KPV peptide?
KPV is the synthetic tripeptide lysine-proline-valine (Lys-Pro-Val). It corresponds to residues 11–13 at the C-terminus of alpha-melanocyte-stimulating hormone (α-MSH), while excluding the parent peptide's central melanocortin pharmacophore.
Published research examines KPV at the cellular level through anti-inflammatory-signaling and immune-modulation endpoints, including NF-κB activation and nuclear translocation, cytokine-expression readouts, and peptide-transporter uptake. These measurements are model-dependent and describe experimental observations rather than outcomes beyond the studied systems. This page identifies the material and those research endpoints only.
KPV COA and batch verification
A Janoshik Analytical report dated June 2026 for KPV 8 mg is on file and displayed with this listing. That report covers an 8 mg sample; it is distinct from the current 10 mg catalog offer and is not presented as documentation for the 10 mg vial. Match the identifier on any received unit through the public batch lookup and review the published verification standards.
KPV research material specifications
| Compound | KPV |
|---|---|
| Sequence | Lys-Pro-Val (KPV); α-MSH residues 11–13 |
| Class | Synthetic tripeptide; C-terminal α-MSH fragment |
| Research focus | Cellular anti-inflammatory-signaling and immune-modulation endpoints |
| Common readouts | NF-κB activation and nuclear translocation, cytokine-expression markers, peptide-transporter uptake |
| Purity specification | ≥99% |
| Physical form | Lyophilized powder in a sealed glass vial |
| Available vial size | 10 mg |
| Attached report | KPV 8 mg — Janoshik Analytical (June 2026); separate from the 10 mg offer |
| Storage | Refrigerated, dry, and protected from light; follow batch documentation |
Cellular signaling research context
Elliott RJ et al., “alpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells” (2004), PMID 15102092. Listed for cellular-signaling context only.
KPV research questions
+What is KPV?
KPV is the tripeptide Lys-Pro-Val, corresponding to residues 11–13 at the C-terminus of alpha-melanocyte-stimulating hormone (α-MSH). It is supplied here strictly as laboratory research material.
+What is the relationship between KPV and α-MSH?
KPV is the three-residue C-terminal fragment of the 13-residue α-MSH sequence. Its compact structure lets researchers examine fragment-level cellular signaling separately from the parent peptide's full melanocortin profile.
+Which KPV research endpoints are commonly examined?
Published cell and model-system studies examine NF-κB activation, nuclear translocation, cytokine-expression readouts, peptide-transporter uptake, and other cellular anti-inflammatory-signaling and immune-modulation endpoints.
+Is KPV a melanocortin pigment peptide?
KPV does not contain the central His-Phe-Arg-Trp melanocortin pharmacophore. Research therefore treats it as a distinct C-terminal fragment rather than as a substitute for the complete α-MSH sequence.
+Is a KPV analytical report available?
Yes. A Janoshik Analytical report dated June 2026 for KPV 8 mg is on file. It documents an 8 mg report only and does not represent the separate 10 mg catalog offer; researchers should match their received unit through the batch lookup.
+Which KPV format is offered?
The current catalog offer is a sealed 10 mg vial of lyophilized research material.
+What limits should be considered when interpreting KPV research?
Cell type, transporter expression, concentration, assay design, and model system can materially affect observed signaling readouts. Results from one experimental system should not be generalized beyond that design.
+What is the listed KPV purity specification?
The catalog specification is ≥99%. A specification is distinct from an individual batch result, so documentation associated with the received unit should be reviewed separately.
Read the KPV research
KPV research overview covering the Lys-Pro-Val sequence, its relationship to α-MSH, NF-κB and cytokine-expression endpoints, transporter uptake, and model limitations.
Read article →What KPV is: the Lys-Pro-Val C-terminal fragment of α-MSH, with cellular-signaling context and research limitations.
Read article →Researcher Reviews
Sign in with the account that placed your order to leave a verified review.
Ask the Lab
No public questions yet — be the first to ask.
Independent Certificate of Analysis
Independently tested by Janoshik Analytical. Verified and batch-tracked by Ares Research. Additional reports available upon request.
No fillers. No shortcuts. Only verified compounds.