
Semax
Documentation & standards
- How to Read a Peptide Certificate of Analysis (COA)
- Peptide Storage and Handling: Temperature, Light and Stability
- Research-Use-Only Compliance: What the Label Obligates
Heptapeptide studied in neurotrophic pathway research.
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Intended strictly for controlled laboratory receptor and pathway research.
What is Semax?
Semax is a synthetic heptapeptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro, constructed from the ACTH(4-10) fragment with an appended Pro-Gly-Pro tripeptide that increases resistance to aminopeptidase cleavage. Unlike the parent hormone, the analog is not reported to drive adrenal-axis activity in the published record.
Laboratory work with Semax examines brain-derived neurotrophic factor (BDNF) and TrkB expression, nerve growth factor (NGF) signalling, melanocortin-receptor interaction, dopaminergic and serotonergic marker changes, and neuroprotective endpoints in ischemia and hypoxia models. These are experimental measurements recorded in research systems only.
This vial listing covers the lyophilized powder format that researchers reconstitute for their own protocol. The pre-formulated solution format is listed separately as Semax nasal spray. No medical, therapeutic, cognitive, or human-use outcome is described or implied for either format.
Semax COA and batch verification
Two Janoshik Analytical reports dated June 2026 are on file for Semax vial material — a general Semax report and a 10 mg report. Each vial carries a batch identifier researchers can use to confirm which documentation corresponds to the material received. The transparency page explains the identity, purity, and documentation framework behind those reports.
Semax research material specifications
| Compound | Semax (ACTH(4-10) analog heptapeptide) |
|---|---|
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Class | Synthetic neuropeptide research material |
| Purity specification | ≥99% |
| Physical form | Lyophilized powder in a sealed glass vial |
| Available vial sizes | 5 mg and 10 mg |
| Research distinction | BDNF/NGF expression, TrkB signalling, and neuroprotective model endpoints |
| Testing | Two Janoshik Analytical reports (June 2026) on file for vial material |
| Storage | Refrigerated, dry, and protected from light; avoid freeze-thaw cycles |
| Origin | Shipped domestically from the USA with tracked delivery |
| Intended scope | Controlled laboratory research only — not for human or veterinary use |
Semax research questions
+What is Semax?
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) built from the ACTH(4-10) fragment with a Pro-Gly-Pro extension that increases resistance to enzymatic cleavage. It is supplied strictly as lyophilized laboratory research material — not for human or veterinary use.
+What is Semax studied for in laboratory research?
Published laboratory work examines BDNF and NGF expression, TrkB signalling, melanocortin-receptor interaction, dopaminergic and serotonergic markers, and neuroprotective endpoints in ischemia and hypoxia models. These are experimental measurements only; no human-use, cognitive, or therapeutic outcome is described or implied.
+How is the Semax vial format different from the nasal spray format?
The vial format is supplied as a sealed lyophilized powder that the researcher reconstitutes for their own protocol. The nasal spray is supplied pre-formulated as a measured-concentration solution. The formats carry different documentation and handling requirements and are listed as separate catalog materials.
+Is a Semax COA on file?
Yes. Two Janoshik Analytical reports dated June 2026 are on file for Semax vial material — one general Semax report and one 10 mg report. Both can be viewed through the public COA lookup, and the transparency page explains the identity and purity documentation framework.
+What purity specification applies to Semax?
The listed purity specification is ≥99%. Researchers should use the batch identifier on the vial to confirm which analytical documentation corresponds to the specific material received rather than treating a general standard as a batch result.
+What vial sizes are available?
Semax is supplied as lyophilized research material in sealed 5 mg and 10 mg vials. Current formats and offers are shown on this page.
+How should sealed Semax be stored, and how does it ship?
Keep the sealed lyophilized vial refrigerated, dry, and protected from light, following its batch documentation, and avoid repeated freeze-thaw cycles. Orders ship domestically from the USA with tracked delivery. The material is intended strictly for controlled laboratory research.
Read the Semax research
What is Semax? ACTH-derived nootropic peptide research mechanisms.
Read article →Two heptapeptides with distinct mechanisms studied in neurotrophic, anxiolytic, and neuroprotective research contexts — a side-by-side examination for laboratory reference.
Read article →