MK-677 (Ibutamoren)
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≥99% purity verified by independent HPLC and mass spectrometry (MS) through Janoshik Analytical. Intended for laboratory research use only; not for human consumption, diagnosis, or treatment. View transparency report Compliance PDFs
Documentation & standards
- How to Read a Peptide Certificate of Analysis (COA)
- Peptide Storage and Handling: Temperature, Light and Stability
- Research-Use-Only Compliance: What the Label Obligates
Ghrelin receptor agonist studied in growth hormone secretagogue research models. Research liquid format.
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Research selection across GH secretagogue, SARM, PPAR-δ and ERR-agonist research models.
Build the full stack →Batch transparency
- Batch / lot
- Released with your order
- Testing lab
- Janoshik Analytical
- Purity (HPLC)
- ≥99% target spec
- Identity (MS)
- Available on request
- Report issued
- Available on request
- Full PDF report
- By request
Every request returns a reference number and a live status page. See all published batch records →
For laboratory research use only — not for human or veterinary use.
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Intended strictly for research and laboratory use only. Not for human consumption.
About MK-677 (Ibutamoren)
Third-party purity testing available upon request.
Research Classification
Storage Information
MK-677 (Ibutamoren) Purity & COA Verification
For laboratory research use only. Not for human consumption, diagnosis, or treatment.
MK-677 (Ibutamoren) — Compound Information & Scientific Literature
Reference data for laboratory personnel: molecular identity, storage and stability handling, our analytical testing panel, and peer-reviewed literature indexed on PubMed.
Molecular Profile
| Compound | MK-677 (Ibutamoren) |
|---|---|
| Molecule type | GH Secretagogue |
| Class | GH Secretagogue |
| Catalog category | Growth Hormone |
| Physical format | Research liquid |
Handling Reference
Not applicable — supplied as a ready solution
See batch label; store sealed at 2-8 °C
2-8 °C (refrigerated), protected from light
Use within the period stated on the batch label once the stopper is punctured
Analytical Testing Panel
Verified by Janoshik Analytical — full panel, every batch. Second independent lab confirmation is being added batch by batch.
Quantifies the main peak against related-substance peaks, so the stated purity percentage is measured rather than assumed.
Every MK-677 (Ibutamoren) lot passes all 8 stages before it is released. Expand a stage to see the method and why we run it.
- Method on the COARP-HPLC (UV 214 nm)Why Ares runs it
Quantifies the main peak against related-substance peaks, so the stated purity percentage is measured rather than assumed.
- Method on the COAQuantitative HPLC mass/concentration assayWhy Ares runs it
Confirms the vial actually contains the labeled amount — purity alone says nothing about how much material is in the vial.
- Method on the COAMass Spectrometry (ESI-MS)Why Ares runs it
Confirms the measured molecular mass matches the declared compound — the check that catches a mislabeled or substituted vial.
- Method on the COAICP-MSWhy Ares runs it
Screens for elemental contaminants carried over from synthesis, reagents, or packaging.
- Method on the COAMembrane filtration, USP <71> methodologyWhy Ares runs it
Checks the finished lyophilized vial for microbial growth after fill and closure.
- Method on the COALAL assay (kinetic chromogenic)Why Ares runs it
Measures bacterial endotoxin load, a contamination marker that purity testing alone will not reveal.
- Method on the COAIndependent batch review against release specificationWhy Ares runs it
Ties the analytical numbers back to the paperwork — the lot you receive is the lot on the certificate.
- Method on the COALC-MS/MS targeted screenWhy Ares runs it
A contamination check most research suppliers never run, and the reason we run it on every batch regardless of compound.
PASS reflects the batch release standard every lot must meet before it ships. Per-lot results are published on that lot's Certificate of Analysis.
Peer-Reviewed References
Oral ghrelin receptor agonist MK-0677 increases serum insulin-like growth factor 1 in hemodialysis patients: a randomized blinded study
Campbell GA et al. · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018 · PMID 28340044
View sourceDevelopment of growth hormone secretagogues
Smith RG · Endocrine reviews, 2005 · PMID 15814848
View sourceMK-0677, a Ghrelin Agonist, Alleviates Amyloid Beta-Related Pathology in 5XFAD Mice, an Animal Model of Alzheimer's Disease
Jeong YO et al. · International journal of molecular sciences, 2018 · PMID 29912176
View sourceGhrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging
Smith RG et al. · Annals of the New York Academy of Sciences, 2007 · PMID 18056963
View sourceNonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling
Holst B et al. · Molecular endocrinology (Baltimore, Md.), 2005 · PMID 15905359
View source
References are listed for literature-identification purposes only. Ares Research is not affiliated with the authors, journals, or institutions cited.
This material is supplied for laboratory and research use only. It is not for human or veterinary use, and it is not a drug, food, or cosmetic. These statements have not been evaluated by the Food and Drug Administration. No information on this page is intended to diagnose, treat, cure, or prevent any condition.
How Ares compares for MK-677 (Ibutamoren)
Independent, documentation-first breakdowns of the vendors researchers most often ask about for this compound. COA verification, US shipping, and sourcing transparency, side by side.
Research Use Disclaimer
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All testing documentation and COA data are provided for laboratory research use only and are not intended to support human consumption, diagnostic, or therapeutic use.
Independent Certificate of Analysis
Independently tested by In-House Verification. Verified and batch-tracked by Ares Research. Additional reports available upon request.
No fillers. No shortcuts. Only verified compounds.
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