
NAD+
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≥99% purity verified by independent HPLC and mass spectrometry (MS) through Janoshik Analytical. Intended for laboratory research use only; not for human consumption, diagnosis, or treatment. View transparency report Compliance PDFs
Documentation & standards
- Peptide Storage and Handling: Temperature, Light and Stability
- How to Read a Peptide Certificate of Analysis (COA)
- Research-Use-Only Compliance: What the Label Obligates
Coenzyme studied in cellular energetics and longevity research.
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Research selection for telomerase, cellular energetics, and mitochondrial pathway studies.
Build the full stack →Batch transparency
- Batch / lot
- Released with your order
- Testing lab
- Janoshik Analytical
- Purity (HPLC)
- ≥99% target spec
- Identity (MS)
- Available on request
- Report issued
- Available on request
- Full PDF report
- By request
Every request returns a reference number and a live status page. See all published batch records →
For laboratory research use only — not for human or veterinary use.
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Intended strictly for research and laboratory use only. Not for human consumption.
About NAD+
Third-party purity testing available upon request.
Research Classification
Storage Information
NAD+ Purity & COA Verification
For laboratory research use only. Not for human consumption, diagnosis, or treatment.
NAD+ COA and third-party testing
Every NAD+ batch is analysed by an independent laboratory before release. HPLC measures purity against a ≥99% standard, mass spectrometry confirms identity, and the published panel records heavy-metals, endotoxin and sterility screening where applicable. The NAD+ certificate of analysis is tied to the batch number printed on the vial, so the result can be verified at source rather than taken from a summary claim.
Testing documentation is supplied for laboratory research use only and does not support human, veterinary, cosmetic, diagnostic or therapeutic use.
What is NAD+?
NAD+ is nicotinamide adenine dinucleotide, a coenzyme present in every living cell. Unlike most of the catalogue, it is not a peptide: it is a dinucleotide formed from nicotinamide mononucleotide and adenosine monophosphate, and it cycles between its oxidised (NAD+) and reduced (NADH) forms as an electron carrier in redox reactions.
That redox cycling places NAD+ at the centre of cellular energy metabolism — glycolysis, the citric acid cycle and oxidative phosphorylation all depend on the NAD+/NADH pool. NAD+ is also consumed as a substrate by sirtuin and PARP enzymes, which is why published laboratory work examines it alongside mitochondrial function, metabolic flux and cellular longevity endpoints in cell and animal models.
Those references describe measurements recorded in research settings only. They do not establish an effect, benefit, anti-ageing outcome or suitability for any person, and nothing here constitutes medical, dosing or therapeutic guidance.
NAD+ product specifications
| Compound | NAD+ — nicotinamide adenine dinucleotide (oxidised form) |
|---|---|
| Class | Coenzyme (pyridine dinucleotide) — not a peptide |
| Purity standard | ≥99% (HPLC, with identity confirmed by mass spectrometry) |
| Physical form | Lyophilised powder in a sealed glass vial |
| Available vial sizes | 100mg, 500mg and 1000mg |
| Storage | Refrigerated and protected from light and moisture; batch handling documentation included |
| Testing | Third-party COA covering identity, purity, heavy metals, endotoxins and sterility |
| Origin | Shipped domestically (USA) with tracked delivery |
| Intended use | Laboratory research use only — not for human or veterinary use |
NAD+ research questions
+What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells. It is not a peptide — it is a dinucleotide built from nicotinamide mononucleotide and adenosine monophosphate, and it functions as an electron carrier in redox reactions that support cellular energy metabolism. It is supplied here as a research compound for laboratory use only.
+Why is NAD+ studied in research?
Published laboratory literature examines NAD+ in the context of mitochondrial function, oxidative phosphorylation, sirtuin and PARP enzyme activity, and cellular longevity endpoints in cell and animal models. These describe measurements recorded in research settings only and do not establish any effect, benefit or outcome for any person.
+Does NAD+ come with a certificate of analysis?
Yes. Every NAD+ batch is released against a third-party certificate of analysis tied to the batch number printed on the vial. You can look the batch up directly through the COA lookup on this site.
+How is NAD+ tested?
Identity and purity are confirmed by HPLC against a ≥99% standard, with mass spectrometry used to confirm identity. The published panel also records heavy-metals, endotoxin and sterility screening where applicable. Testing is performed by an independent laboratory, not in-house.
+What purity is the NAD+?
NAD+ is released to a ≥99% HPLC purity specification. The measured figure for the batch you receive is recorded on that batch's certificate of analysis rather than quoted as a generic claim.
+What vial sizes are available?
NAD+ is available in 100mg, 500mg and 1000mg lyophilised vials.
+How should NAD+ be stored?
Sealed lyophilised vials are stored refrigerated and protected from light. NAD+ is sensitive to moisture and light, so vials should be kept sealed until use and handled under standard laboratory conditions. Batch handling documentation is included.
+Where does NAD+ ship from?
NAD+ is shipped domestically within the USA with tracked delivery. Batch documentation ships with the order.
+Is NAD+ intended for human use?
No. NAD+ sold here is supplied strictly for laboratory research use. It is not for human or veterinary use, is not a drug, food or cosmetic, and has not been evaluated by the FDA for any use.
NAD+ — Compound Information & Scientific Literature
Reference data for laboratory personnel: molecular identity, storage and stability handling, our analytical testing panel, and peer-reviewed literature indexed on PubMed.
Molecular Profile
| Compound | NAD+ |
|---|---|
| Molecule type | Coenzyme |
| Class | Coenzyme |
| Catalog category | Wellness |
| Physical format | Lyophilized vial |
Handling Reference
-20 °C, protected from light and moisture
24 months from date of manufacture in the sealed vial
2-8 °C (refrigerated), do not freeze after reconstitution
Stability studied out to approximately 28 days under continuous refrigeration
Analytical Testing Panel
Verified by Janoshik Analytical — full panel, every batch. Second independent lab confirmation is being added batch by batch.
Quantifies the main peak against related-substance peaks, so the stated purity percentage is measured rather than assumed.
Every NAD+ lot passes all 8 stages before it is released. Expand a stage to see the method and why we run it.
- Method on the COARP-HPLC (UV 214 nm)Why Ares runs it
Quantifies the main peak against related-substance peaks, so the stated purity percentage is measured rather than assumed.
- Method on the COAQuantitative HPLC mass/concentration assayWhy Ares runs it
Confirms the vial actually contains the labeled amount — purity alone says nothing about how much material is in the vial.
- Method on the COAMass Spectrometry (ESI-MS)Why Ares runs it
Confirms the measured molecular mass matches the declared compound — the check that catches a mislabeled or substituted vial.
- Method on the COAICP-MSWhy Ares runs it
Screens for elemental contaminants carried over from synthesis, reagents, or packaging.
- Method on the COAMembrane filtration, USP <71> methodologyWhy Ares runs it
Checks the finished lyophilized vial for microbial growth after fill and closure.
- Method on the COALAL assay (kinetic chromogenic)Why Ares runs it
Measures bacterial endotoxin load, a contamination marker that purity testing alone will not reveal.
- Method on the COAIndependent batch review against release specificationWhy Ares runs it
Ties the analytical numbers back to the paperwork — the lot you receive is the lot on the certificate.
- Method on the COALC-MS/MS targeted screenWhy Ares runs it
A contamination check most research suppliers never run, and the reason we run it on every batch regardless of compound.
PASS reflects the batch release standard every lot must meet before it ships. Per-lot results are published on that lot's Certificate of Analysis.
Peer-Reviewed References
NAD(+) metabolism and its roles in cellular processes during ageing
Covarrubias AJ et al. · Nature reviews. Molecular cell biology, 2021 · PMID 33353981
View sourceNAD⁺ in aging, metabolism, and neurodegeneration
Verdin E · Science (New York, N.Y.), 2015 · PMID 26785480
View sourceThe Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update
Song Q et al. · Advances in nutrition (Bethesda, Md.), 2023 · PMID 37619764
View sourceNAD(+) metabolism: pathophysiologic mechanisms and therapeutic potential
Xie N et al. · Signal transduction and targeted therapy, 2020 · PMID 33028824
View sourceNAD(+) homeostasis in health and disease
Katsyuba E et al. · Nature metabolism, 2020 · PMID 32694684
View source
References are listed for literature-identification purposes only. Ares Research is not affiliated with the authors, journals, or institutions cited.
This material is supplied for laboratory and research use only. It is not for human or veterinary use, and it is not a drug, food, or cosmetic. These statements have not been evaluated by the Food and Drug Administration. No information on this page is intended to diagnose, treat, cure, or prevent any condition.
Read the NAD+ research
MOTS-c vs NAD+ for mitochondrial research: AMPK signaling vs sirtuin cofactor supply, dosing routes and metabolic endpoints.
Read article →NAD+ safety profile: infusion reactions, flushing, gastrointestinal effects, and monitoring for IV and subcutaneous routes.
Read article →Nicotinamide adenine dinucleotide as a subject of cellular energetics and longevity research — mechanisms, precursor pathways, and the current evidence base for intervention studies.
Read article →Research guide on Nicotinamide Adenine Dinucleotide (NAD+): sirtuin and PARP cofactor biology, age-related decline, precursor comparisons (NMN, NR), and the documented side-effect profile.
Read article →Compare Epitalon tetrapeptide and NAD+ coenzyme research in cellular aging and longevity models.
Read article →Cellular pharmacology of NAD+ supplementation: redox cofactor role, sirtuin and PARP substrate function, CD38 consumption pathway, and the case for precursor (NR/NMN) vs direct NAD+ administration.
Read article →How Ares compares for NAD+
Independent, documentation-first breakdowns of the vendors researchers most often ask about for this compound. COA verification, US shipping, and sourcing transparency, side by side.
Frequently bought together
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Research Use Disclaimer
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All testing documentation and COA data are provided for laboratory research use only and are not intended to support human consumption, diagnostic, or therapeutic use.
Independent Certificate of Analysis
Independently tested by Janoshik Analytical. Verified and batch-tracked by Ares Research. Additional reports available upon request.
No fillers. No shortcuts. Only verified compounds.
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